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Chronic lymphocytic leukemia

CAMK2D · rs6858698

Where this position leads

Condition: Chronic Lymphocytic Leukaemia

rs6858698 Condition: Chronic Lymphocytic Leukaemia Chronic Lymphocytic Leukaemia Condition rs6858698 rs6858698 CAMK2D

What the study found

Who was studied 1,739 European ancestry cases, 5,199 European ancestry controls; replicated in 1,144 European ancestry cases, 3,151 European ancestry controls.

The effect Each copy of the C allele carried 1.31 times the odds of Chronic lymphocytic leukemia (95% confidence interval 1.20-1.44); p = 3 × 10−9.

Where it sits Chromosome 4, band 4q26 — between genes, 0.8 kb from CAMK2D.

What each result means

C/C Two copies of the version the research linked to Chronic lymphocytic leukemia. That is the strongest link of the three results. A link in a study is not a diagnosis.
C/G One copy of the version the research linked to Chronic lymphocytic leukemia. That is a smaller link than two copies.
G/G No copy of the version the research linked to Chronic lymphocytic leukemia. This is the starting point the study compared everyone against.
Source

Questions about rs6858698

What is rs6858698?

rs6858698 is a single position in the genome, in or near the CAMK2D gene. Published research associates it with chronic lymphocytic leukemia. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

What conditions is rs6858698 linked to?

On MyGeneLog this position is linked to Chronic Lymphocytic Leukaemia. The research behind each link, and its sources, are set out on that condition page.

Does having rs6858698 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs6858698 come from?

GWAS Catalog, Nat Genet 2013, PMID:24292274. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

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Chronic lymphocytic leukemia (rs6858698). MyGeneLog™. https://www.mygenelog.com/variants/rs6858698

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