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Who was studied 532 Korean ancestry cases, 733 Korean ancestry controls; replicated in 1,779 Korean ancestry cases, 1,709 Korean ancestry controls.
The effect
Each copy of the C allele carried 1.43 times the odds of Crohn's disease (95% confidence interval 1.31-1.57); p = 4 × 10−14.
How common The C allele had a frequency of about 23% in the people studied.
Where it sits Chromosome 4, band 4p14 — in an intron of LINC02513.
What each result means
C/CTwo copies of the version the research linked to Crohn's disease. That is the strongest link of the three results. A link in a study is not a diagnosis.
C/TOne copy of the version the research linked to Crohn's disease. That is a smaller link than two copies.
T/TNo copy of the version the research linked to Crohn's disease. This is the starting point the study compared everyone against.
rs6856616 is a single position in the genome, in or near the KLF3 gene. Published research associates it with crohn's disease. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.
What conditions is rs6856616 linked to?
On MyGeneLog this position is linked to Crohn's Disease. The research behind each link, and its sources, are set out on that condition page.
Does having rs6856616 mean I will get this?
No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.
Where does the information about rs6856616 come from?
GWAS Catalog, Gut 2013, PMID:23850713. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.
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