Standard

Post bronchodilator FEV1/FVC ratio

near KRT18P51 · rs6842889

Where this position leads

Condition: Pulmonary Function (Lung Capacity)

rs6842889 Condition: Pulmonary Function (Lung Capacity) Pulmonary Function (Lung Capacity) Condition rs6842889 rs6842889 near KRT18P51

What the study found

Who was studied 10,094 European ancestry current and former smoker individuals, 3,260 African American current and former smoker individuals, 178 current and former smoker individuals.

The effect Each copy of the T allele shifted the measure 0.016 lower; p = 4 × 10−16.

How common The T allele had a frequency of about 65% in the people studied.

Where it sits Chromosome 4, band 4q31.21 — between genes, 13.5 kb from KRT18P51.

What each result means

C/C No copy of the version the research linked to Post bronchodilator FEV1/FVC ratio. This is the starting point the study compared everyone against.
C/T One copy of the version the research linked to Post bronchodilator FEV1/FVC ratio. That is a smaller link than two copies.
T/T Two copies of the version the research linked to Post bronchodilator FEV1/FVC ratio. That is the strongest link of the three results. A link in a study is not a diagnosis.
Source

Questions about rs6842889

What is rs6842889?

rs6842889 is a single position in the genome, in or near the near KRT18P51 gene. Published research associates it with post bronchodilator fev1/fvc ratio. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

What conditions is rs6842889 linked to?

On MyGeneLog this position is linked to Pulmonary Function (Lung Capacity). The research behind each link, and its sources, are set out on that condition page.

Does having rs6842889 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs6842889 come from?

GWAS Catalog, BMC genetics 2015, PMID:26634245. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

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Post bronchodilator FEV1/FVC ratio (rs6842889). MyGeneLog™. https://www.mygenelog.com/variants/rs6842889

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