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Who was studied 418,642 British ancestry individuals.
The effect
Each copy of the C allele shifted the measure 0.0127 lower (95% confidence interval 0.0088-0.0167); p = 2 × 10−10.
How common The C allele had a frequency of about 49% in the people studied.
Where it sits Chromosome 1, band 1p36.22 — in an intron of PEX14.
What each result means
A/ANo copy of the version the research linked to C-reactive protein levels. This is the starting point the study compared everyone against.
A/COne copy of the version the research linked to C-reactive protein levels. That is a smaller link than two copies.
C/CTwo copies of the version the research linked to C-reactive protein levels. That is the strongest link of the three results. A link in a study is not a diagnosis.
European journal of epidemiology · 2020 · PMID 31900758
Questions about rs684016
What is rs684016?
rs684016 is a single position in the genome, in or near the PEX14 gene. Published research associates it with c-reactive protein levels. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.
What conditions is rs684016 linked to?
On MyGeneLog this position is linked to C-Reactive Protein Levels. The research behind each link, and its sources, are set out on that condition page.
Does having rs684016 mean I will get this?
No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.
Where does the information about rs684016 come from?
GWAS Catalog, European journal of epidemiology 2020, PMID:31900758. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.
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Quoting this page
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C-reactive protein levels (rs684016). MyGeneLog™. https://www.mygenelog.com/variants/rs684016