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Atrial fibrillation (MTAG)

ARHGAP10 · rs6839459

Where this position leads

Condition: Atrial Fibrillation

rs6839459 Condition: Atrial Fibrillation Atrial Fibrillation Condition rs6839459 rs6839459 ARHGAP10

What the study found

Who was studied 1,030,836 European ancestry individuals.

The effect Each copy of the A allele shifted the measure 0.019 lower (95% confidence interval 0.013-0.025); p = 5 × 10−11.

Where it sits Chromosome 4, band 4q31.23 — in an intron of ARHGAP10.

What each result means

A/A Two copies of the version the research linked to Atrial fibrillation (MTAG). That is the strongest link of the three results. A link in a study is not a diagnosis.
A/G One copy of the version the research linked to Atrial fibrillation (MTAG). That is a smaller link than two copies.
G/G No copy of the version the research linked to Atrial fibrillation (MTAG). This is the starting point the study compared everyone against.
Source

Questions about rs6839459

What is rs6839459?

rs6839459 is a single position in the genome, in or near the ARHGAP10 gene. Published research associates it with atrial fibrillation (mtag). A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

What conditions is rs6839459 linked to?

On MyGeneLog this position is linked to Atrial Fibrillation. The research behind each link, and its sources, are set out on that condition page.

Does having rs6839459 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs6839459 come from?

GWAS Catalog, Frontiers in cardiovascular medicine 2022, PMID:35872910. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

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Atrial fibrillation (MTAG) (rs6839459). MyGeneLog™. https://www.mygenelog.com/variants/rs6839459

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