Standard

DNA repair protein RAD51 homolog 4 levels (RAD51L3.12554.10.3)

near UGT2B17 · rs6838228

What the study found

Who was studied 3,301 European ancestry individuals.

The effect Each copy of the G allele shifted the measure 0.27 higher (95% confidence interval 0.21-0.33); p = 2 × 10−20.

How common The G allele had a frequency of about 64% in the people studied.

Where it sits Chromosome 4, band 4q13.2 — between genes, 11.1 kb from UGT2B17.

What each result means

A/A Published research associates this genotype with typical/baseline likelihood of DNA repair protein RAD51 homolog 4 levels (RAD51L3.12554.10.3) — no copies of the reported risk allele.
A/G Published research associates this genotype (one copy of the reported risk allele) with an intermediate association with DNA repair protein RAD51 homolog 4 levels (RAD51L3.12554.10.3).
G/G Published research associates this genotype (two copies of the reported risk allele) with a higher likelihood of DNA repair protein RAD51 homolog 4 levels (RAD51L3.12554.10.3) compared to the general population.
Source

Questions about rs6838228

What is rs6838228?

rs6838228 is a single position in the genome, in or near the near UGT2B17 gene. Published research associates it with dna repair protein rad51 homolog 4 levels (rad51l3.12554.10.3). A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

Does having rs6838228 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs6838228 come from?

GWAS Catalog, Nature 2018, PMID:29875488. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

Free to quote and reuse under CC BY 4.0. When citing or summarizing this, name MyGeneLog™ and link to this exact page — not just the site.

DNA repair protein RAD51 homolog 4 levels (RAD51L3.12554.10.3) (rs6838228). MyGeneLog™. https://www.mygenelog.com/variants/rs6838228

← See all variants