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Liver enzyme levels (alanine transaminase)

HSD17B13 · rs6834314

What the study found

Who was studied Up to 52,350 European ancestry individuals, up to 8,739 Indian Asian ancestry individuals.

The effect Each copy of the A allele shifted the measure 2.6 % higher (95% confidence interval 1.90-3.40); p = 3 × 10−9.

How common The A allele had a frequency of about 75% in the people studied.

Where it sits Chromosome 4, band 4q22.1 — between genes, 7.8 kb from MIR5705.

What each result means

A/A Two copies of the version the research linked to Liver enzyme levels (alanine transaminase). That is the strongest link of the three results. A link in a study is not a diagnosis.
A/G One copy of the version the research linked to Liver enzyme levels (alanine transaminase). That is a smaller link than two copies.
G/G No copy of the version the research linked to Liver enzyme levels (alanine transaminase). This is the starting point the study compared everyone against.
Source

What people read about alongside this

Papers in Europe PMC whose title or abstract names both this rsID and that subject. A shared paper means somebody wrote about the two together — it is not a claim that this position explains the subject.

Questions about rs6834314

What is rs6834314?

rs6834314 is a single position in the genome, in or near the HSD17B13 gene. Published research associates it with liver enzyme levels (alanine transaminase). A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

What do people read about alongside rs6834314?

Subjects that appear in the title or abstract of the same papers as this rsID include liver (4 papers), blood sugar and insulin (2 papers), alcohol and the flush (1 papers), caffeine and energy drinks (1 papers). A shared paper means somebody wrote about the two together; it is not a claim that this position explains the topic.

Does having rs6834314 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs6834314 come from?

GWAS Catalog, Nat Genet 2011, PMID:22001757. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

Free to quote and reuse under CC BY 4.0. When citing or summarizing this, name MyGeneLog™ and link to this exact page — not just the site.

Liver enzyme levels (alanine transaminase) (rs6834314). MyGeneLog™. https://www.mygenelog.com/variants/rs6834314

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