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Cotinine glucuronidation

OC255130 · rs6832720

Where this position leads

Condition: Nicotine and Cotinine Metabolism

rs6832720 Condition: Nicotine and Cotinine Metabolism Nicotine and Cotinine Metabolism Condition rs6832720 rs6832720 OC255130

What the study found

Who was studied 437 European ancestry current smoker individuals, 364 African American current smoker individuals, 453 Latino current smoker individuals, 674 Japanese ancestry current smoker individuals, 311 Native Hawaiian ancestry current smoker individuals.

The effect Each copy of the A allele shifted the measure 0.0585 lower; p = 7 × 10−9.

Where it sits Chromosome 4, band 4q12 — between genes, 70.8 kb from RPS26P24.

What each result means

A/A Two copies of the version the research linked to Cotinine glucuronidation. That is the strongest link of the three results. A link in a study is not a diagnosis.
A/G One copy of the version the research linked to Cotinine glucuronidation. That is a smaller link than two copies.
G/G No copy of the version the research linked to Cotinine glucuronidation. This is the starting point the study compared everyone against.
Source

Questions about rs6832720

What is rs6832720?

rs6832720 is a single position in the genome, in or near the OC255130 gene. Published research associates it with cotinine glucuronidation. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

What conditions is rs6832720 linked to?

On MyGeneLog this position is linked to Nicotine and Cotinine Metabolism. The research behind each link, and its sources, are set out on that condition page.

Does having rs6832720 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs6832720 come from?

GWAS Catalog, Cancer Epidemiol Biomarkers Prev 2014, PMID:25293881. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

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Cotinine glucuronidation (rs6832720). MyGeneLog™. https://www.mygenelog.com/variants/rs6832720

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