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Who was studied at least 20,352 European ancestry cases, at least 31,358 European ancestry controls.
The effect
Each copy of the T allele shifted the measure 0.211 higher (95% confidence interval 0.17-0.25); p = 2 × 10−21.
How common The T allele had a frequency of about 93% in the people studied.
Where it sits Chromosome 6, band 6p22.1 — in an intron of ZSCAN16.
What each result means
C/CNo copy of the version the research linked to Bipolar disorder (MTAG). This is the starting point the study compared everyone against.
C/TOne copy of the version the research linked to Bipolar disorder (MTAG). That is a smaller link than two copies.
T/TTwo copies of the version the research linked to Bipolar disorder (MTAG). That is the strongest link of the three results. A link in a study is not a diagnosis.
Translational psychiatry · 2021 · PMID 33479212 · open access
Questions about rs68188794
What is rs68188794?
rs68188794 is a single position in the genome, in or near the ZSCAN16 gene. Published research associates it with bipolar disorder (mtag). A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.
What conditions is rs68188794 linked to?
On MyGeneLog this position is linked to Bipolar Disorder. The research behind each link, and its sources, are set out on that condition page.
Does having rs68188794 mean I will get this?
No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.
Where does the information about rs68188794 come from?
GWAS Catalog, Translational psychiatry 2021, PMID:33479212. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.
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