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Total cholesterol levels

JAZF1 · rs68183954

What the study found

Who was studied 153,950 Korean ancestry individuals.

The effect Each copy of the T allele shifted the measure 0.0233 higher (95% confidence interval 0.016-0.031); p = 3 × 10−10.

How common The T allele had a frequency of about 39% in the people studied.

Where it sits Chromosome 7, band 7p15.1 — in an intron of JAZF1.

What each result means

C/C Published research associates this genotype with typical/baseline likelihood of Total cholesterol levels — no copies of the reported risk allele.
C/T Published research associates this genotype (one copy of the reported risk allele) with an intermediate association with Total cholesterol levels.
T/T Published research associates this genotype (two copies of the reported risk allele) with a higher likelihood of Total cholesterol levels compared to the general population.
Source

Questions about rs68183954

What is rs68183954?

rs68183954 is a single position in the genome, in or near the JAZF1 gene. Published research associates it with total cholesterol levels. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

Does having rs68183954 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs68183954 come from?

GWAS Catalog, Nature communications 2025, PMID:40436827. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

Free to quote and reuse under CC BY 4.0. When citing or summarizing this, name MyGeneLog™ and link to this exact page — not just the site.

Total cholesterol levels (rs68183954). MyGeneLog™. https://www.mygenelog.com/variants/rs68183954

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