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Aspartate aminotransferase levels

near HNRNPA1P31 · rs68177066

What the study found

Who was studied 424,778 European ancestry individuals.

The effect Each copy of the C allele shifted the measure 0.014 U/L lower; p = 6 × 10−12.

How common The C allele had a frequency of about 34% in the people studied.

Where it sits Chromosome 13, band 13q31.1 — between genes, 89 kb from HNRNPA1P31.

What each result means

C/C Two copies of the version the research linked to Aspartate aminotransferase levels. That is the strongest link of the three results. A link in a study is not a diagnosis.
C/T One copy of the version the research linked to Aspartate aminotransferase levels. That is a smaller link than two copies.
T/T No copy of the version the research linked to Aspartate aminotransferase levels. This is the starting point the study compared everyone against.
Source

Questions about rs68177066

What is rs68177066?

rs68177066 is a single position in the genome, in or near the near HNRNPA1P31 gene. Published research associates it with aspartate aminotransferase levels. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

Does having rs68177066 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs68177066 come from?

GWAS Catalog, Diabetes 2021, PMID:33980691. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

Free to quote and reuse under CC BY 4.0. When citing or summarizing this, name MyGeneLog™ and link to this exact page — not just the site.

Aspartate aminotransferase levels (rs68177066). MyGeneLog™. https://www.mygenelog.com/variants/rs68177066

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