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Gout

near WDR1 · rs6811287

Where this position leads

Condition: Gout

rs6811287 Condition: Gout Gout Condition rs6811287 rs6811287 near WDR1

What the study found

Who was studied 7,131 European ancestry cases, 325,239 European ancestry controls.

The effect Each copy of the C allele carried 1.14 times the odds of Gout (95% confidence interval 1.1-1.19); p = 9 × 10−12.

How common The C allele had a frequency of about 55% in the people studied.

Where it sits Chromosome 4, band 4p16.1 — between genes, 62.2 kb from WDR1.

What each result means

C/C Two copies of the version the research linked to Gout. That is the strongest link of the three results. A link in a study is not a diagnosis.
C/T One copy of the version the research linked to Gout. That is a smaller link than two copies.
T/T No copy of the version the research linked to Gout. This is the starting point the study compared everyone against.
Source

Questions about rs6811287

What is rs6811287?

rs6811287 is a single position in the genome, in or near the near WDR1 gene. Published research associates it with gout. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

What conditions is rs6811287 linked to?

On MyGeneLog this position is linked to Gout. The research behind each link, and its sources, are set out on that condition page.

Does having rs6811287 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs6811287 come from?

GWAS Catalog, Arthritis & rheumatology (Hoboken, N.J.) 2023, PMID:36281732. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

Free to quote and reuse under CC BY 4.0. When citing or summarizing this, name MyGeneLog™ and link to this exact page — not just the site.

Gout (rs6811287). MyGeneLog™. https://www.mygenelog.com/variants/rs6811287

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