Sensitive

Brugada syndrome

EXOG · rs6810361

Where this position leads

Condition: Brugada Syndrome

rs6810361 Condition: Brugada Syndrome Brugada Syndrome Condition rs6810361 rs6810361 EXOG

What the study found

Who was studied 940 East Asian ancestry cases, 1,634 East Asian ancestry controls.

The effect Each copy of the C allele carried 1.70 times the odds of Brugada syndrome (95% confidence interval 1.5-1.94); p = 4 × 10−16.

How common The C allele had a frequency of about 42% in the people studied.

Where it sits Chromosome 3, band 3p22.2 — in a regulatory region of EXOG.

What each result means

C/C Two copies of the version the research linked to Brugada syndrome. That is the strongest link of the three results. A link in a study is not a diagnosis.
C/T One copy of the version the research linked to Brugada syndrome. That is a smaller link than two copies.
T/T No copy of the version the research linked to Brugada syndrome. This is the starting point the study compared everyone against.
Source

Questions about rs6810361

What is rs6810361?

rs6810361 is a single position in the genome, in or near the EXOG gene. Published research associates it with brugada syndrome. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

What conditions is rs6810361 linked to?

On MyGeneLog this position is linked to Brugada Syndrome. The research behind each link, and its sources, are set out on that condition page.

Does having rs6810361 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs6810361 come from?

GWAS Catalog, European heart journal 2024, PMID:38747976. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

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Brugada syndrome (rs6810361). MyGeneLog™. https://www.mygenelog.com/variants/rs6810361

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