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Who was studied 25,662 British ancestry cases, 17,928 British ancestry controls; replicated in 13,367 European ancestry cases, 11,851 European ancestry controls, 3,436 cases, 2,435 controls.
The effect
Each copy of the G allele shifted the measure 0.152 higher (95% confidence interval 0.12-0.19); p = 1 × 10−18.
Where it sits Chromosome 21, band 21q22.12 — in an intron of RUNX1.
What each result means
A/ANo copy of the version the research linked to Male-pattern baldness. This is the starting point the study compared everyone against.
A/GOne copy of the version the research linked to Male-pattern baldness. That is a smaller link than two copies.
G/GTwo copies of the version the research linked to Male-pattern baldness. That is the strongest link of the three results. A link in a study is not a diagnosis.
Nature communications · 2017 · PMID 29146897 · open access
Questions about rs68088846
What is rs68088846?
rs68088846 is a single position in the genome, in or near the RUNX1 gene. Published research associates it with male-pattern baldness. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.
What conditions is rs68088846 linked to?
On MyGeneLog this position is linked to Androgenetic Alopecia (Male Pattern Baldness). The research behind each link, and its sources, are set out on that condition page.
Does having rs68088846 mean I will get this?
No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.
Where does the information about rs68088846 come from?
GWAS Catalog, Nat Commun 2017, PMID:29146897. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.
0 3521823217Reads by AI crawlersClaude0ChatGPT2Google · Gemini0Perplexity1Meta AI8Microsoft · Copilot0Amazon2Apple3China (ByteDance, Huawei, Baidu…)2ByteDance (Doubao)2Others17Total35Counted by the name each crawler declares; requests found to be impersonating one are left out. Google · Gemini includes Googlebot, the search crawler whose index Google also uses for its AI features. Other search engines and bots are under Others.
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