Standard

Body mass index

near IGF2BP1 · rs68085814

Where this position leads

Conditions: Childhood Body Mass Index, Obesity and Body Weight

rs68085814 Condition: Childhood Body Mass Index Childhood Body Mass Index Condition Condition: Obesity and Body Weight Obesity and Body Weight Condition rs68085814 rs68085814 near IGF2BP1

What the study found

Who was studied 342,566 European ancestry individuals.

The effect Each copy of the A allele shifted the measure 0.0199 lower (95% confidence interval 0.015-0.025); p = 4 × 10−14.

Where it sits Chromosome 17, band 17q21.32 — between genes, 2.4 kb from IGF2BP1.

What each result means

A/A Two copies of the version the research linked to Body mass index. That is the strongest link of the three results. A link in a study is not a diagnosis.
A/G One copy of the version the research linked to Body mass index. That is a smaller link than two copies.
G/G No copy of the version the research linked to Body mass index. This is the starting point the study compared everyone against.
Source

Questions about rs68085814

What is rs68085814?

rs68085814 is a single position in the genome, in or near the near IGF2BP1 gene. Published research associates it with body mass index. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

What conditions is rs68085814 linked to?

On MyGeneLog this position is linked to Childhood Body Mass Index, Obesity and Body Weight. The research behind each link, and its sources, are set out on that condition page.

Does having rs68085814 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs68085814 come from?

GWAS Catalog, Scientific reports 2024, PMID:38538606. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

Free to quote and reuse under CC BY 4.0. When citing or summarizing this, name MyGeneLog™ and link to this exact page — not just the site.

Body mass index (rs68085814). MyGeneLog™. https://www.mygenelog.com/variants/rs68085814

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