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Who was studied 2,743 Chinese ancestry cases, 3,573 Chinese ancestry controls; replicated in 5,413 Han Chinese ancestry cases, 12,037 Han Chinese ancestry controls.
The effect
Each copy of the T allele carried 1.12 times the odds of Leprosy (95% confidence interval -); p = 2 × 10−8.
How common The T allele had a frequency of about 50% in the people studied.
Where it sits Chromosome 3, band 3p25.2 — between genes, 13.9 kb from GSTM5P1.
What each result means
C/CNo copy of the version the research linked to Leprosy. This is the starting point the study compared everyone against.
C/TOne copy of the version the research linked to Leprosy. That is a smaller link than two copies.
T/TTwo copies of the version the research linked to Leprosy. That is the strongest link of the three results. A link in a study is not a diagnosis.
Nature communications · 2016 · PMID 27976721 · open access
Questions about rs6807915
What is rs6807915?
rs6807915 is a single position in the genome, in or near the SYN2 gene. Published research associates it with leprosy. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.
What conditions is rs6807915 linked to?
On MyGeneLog this position is linked to Leprosy. The research behind each link, and its sources, are set out on that condition page.
Does having rs6807915 mean I will get this?
No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.
Where does the information about rs6807915 come from?
GWAS Catalog, Nat Commun 2016, PMID:27976721. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.
2 373232423117Reads by AI crawlersClaude3ChatGPT2Google · Gemini3Perplexity2Meta AI4Microsoft · Copilot0Amazon2Apple3China (ByteDance, Huawei, Baidu…)1ByteDance (Doubao)1Others17Total37Counted by the name each crawler declares; requests found to be impersonating one are left out. Google · Gemini includes Googlebot, the search crawler whose index Google also uses for its AI features. Other search engines and bots are under Others.
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