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Dilated cardiomyopathy (MTAG)

LSM3 · rs6807275

Where this position leads

Condition: Dilated Cardiomyopathy

rs6807275 Condition: Dilated Cardiomyopathy Dilated Cardiomyopathy Condition rs6807275 rs6807275 LSM3

What the study found

Who was studied 5,521 cases, 397,323 controls.

The effect The reported allele is G; the catalogue records no effect size ; p = 9 × 10−9.

How common The G allele had a frequency of about 66% in the people studied.

Where it sits Chromosome 3, band 3p25.1 — between genes, 31.8 kb from LSM3.

What each result means

A/A No copy of the version the research linked to Dilated cardiomyopathy (MTAG). This is the starting point the study compared everyone against.
A/G One copy of the version the research linked to Dilated cardiomyopathy (MTAG). That is a smaller link than two copies.
G/G Two copies of the version the research linked to Dilated cardiomyopathy (MTAG). That is the strongest link of the three results. A link in a study is not a diagnosis.
Source

Questions about rs6807275

What is rs6807275?

rs6807275 is a single position in the genome, in or near the LSM3 gene. Published research associates it with dilated cardiomyopathy (mtag). A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

What conditions is rs6807275 linked to?

On MyGeneLog this position is linked to Dilated Cardiomyopathy. The research behind each link, and its sources, are set out on that condition page.

Does having rs6807275 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs6807275 come from?

GWAS Catalog, Nature genetics 2021, PMID:33495596. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

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Dilated cardiomyopathy (MTAG) (rs6807275). MyGeneLog™. https://www.mygenelog.com/variants/rs6807275

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