Standard

Atopic dermatitis (moderate to severe)

near GOLGA4 · rs6799780

Where this position leads

What the study found

Who was studied 222 South East Asian ancestry, East Asian ancestry, South Asian ancestry, African American or Afro-Caribbean, European ancestry, Greater Middle Eastern (Middle Eastern, North African or Persian) cases, 2,466 Greater Middle Eastern (Middle Eastern, North African or Persian), Hispanic or Latin American, NR moderate to severe atopic dermatitis cases, 2,466 South East Asian ancestry, East Asian ancestry, South Asian ancestry, African American or Afro-Caribbean, European ancestry, Greater Middle Eastern (Middle Eastern, North African or Persian) cases, 2,466 Greater Middle Eastern (Middle Eastern, North African or Persian), Hispanic or Latin American, NR controls without moderate to severe atopic dermatitis.

The effect Each copy of the G allele shifted the measure 1.19 higher (95% confidence interval 0.957-1.42); p = 7 × 10⁻²⁴.

Where it sits Chromosome 3, band 3p22.2 — between genes, 2.3 kb from GOLGA4.

What each result means

G/G Two copies of the version the research linked to Atopic dermatitis (moderate to severe). That is the strongest link of the three results. A link in a study is not a diagnosis.

G/T One copy of the version the research linked to Atopic dermatitis (moderate to severe). That is a smaller link than two copies.

T/T No copy of the version the research linked to Atopic dermatitis (moderate to severe). This is the starting point the study compared everyone against.

Source

Polygenic risk score for atopic dermatitis in the Canadian population

Simard M, Madore AM, Girard S, Waserman S, Duan Q, Subbarao P, Sears MR, Moraes TJ, Becker AB, Turvey SE, Mandhane PJ, Morin C

and 2 more — show all

Bégin P, Laprise C

The Journal of allergy and clinical immunology · 2021 · PMID 32439431

Questions about rs6799780

What is rs6799780?

rs6799780 is a single position in the genome, in or near the near GOLGA4 gene. Published research associates it with atopic dermatitis (moderate to severe). A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

What conditions is rs6799780 linked to?

On MyGeneLog this position is linked to Atopic Dermatitis. The research behind each link, and its sources, are set out on that condition page.

Does having rs6799780 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs6799780 come from?

GWAS Catalog, The Journal of allergy and clinical immunology 2021, PMID:32439431. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

Free to quote and reuse under CC BY 4.0. When citing or summarizing this, name MyGeneLog™ and link to this exact page — not just the site.

Atopic dermatitis (moderate to severe) (rs6799780). MyGeneLog™. https://www.mygenelog.com/variants/rs6799780

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