Sensitive

COVID-19 or type 2 diabetes (pleiotropy)

ADCY5 · rs6798189

Where this position leads

Condition: Type 2 Diabetes

rs6798189 Condition: Type 2 Diabetes Type 2 Diabetes Condition rs6798189 rs6798189 ADCY5

What the study found

Who was studied up to 2,244 European ancestry critical COVID-19 cases, 26,676 European ancestry T2D cases, up to 137,848 European ancestry controls.

The effect The reported allele is G; the catalogue records no effect size ; p = 1 × 10−10.

Where it sits Chromosome 3, band 3q21.1 — in an intron of ADCY5.

What each result means

A/A No copy of the version the research linked to COVID-19 or type 2 diabetes (pleiotropy). This is the starting point the study compared everyone against.
A/G One copy of the version the research linked to COVID-19 or type 2 diabetes (pleiotropy). That is a smaller link than two copies.
G/G Two copies of the version the research linked to COVID-19 or type 2 diabetes (pleiotropy). That is the strongest link of the three results. A link in a study is not a diagnosis.
Source

Questions about rs6798189

What is rs6798189?

rs6798189 is a single position in the genome, in or near the ADCY5 gene. Published research associates it with covid-19 or type 2 diabetes (pleiotropy). A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

What conditions is rs6798189 linked to?

On MyGeneLog this position is linked to Type 2 Diabetes. The research behind each link, and its sources, are set out on that condition page.

Does having rs6798189 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs6798189 come from?

GWAS Catalog, Frontiers in microbiology 2022, PMID:36187959. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

Free to quote and reuse under CC BY 4.0. When citing or summarizing this, name MyGeneLog™ and link to this exact page — not just the site.

COVID-19 or type 2 diabetes (pleiotropy) (rs6798189). MyGeneLog™. https://www.mygenelog.com/variants/rs6798189

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