Sensitive

Cutaneous squamous cell carcinoma

TPRG1 · rs6791479

Where this position leads

Condition: Cutaneous Squamous Cell Carcinoma

rs6791479 Condition: Cutaneous Squamous Cell Carcinoma Cutaneous Squamous Cell Carcinoma Condition rs6791479 rs6791479 TPRG1

What the study found

Who was studied 19,149 European ancestry cases, 680,049 European ancestry controls.

The effect Each copy of the T allele shifted the measure 0.09 higher (95% confidence interval 0.07-0.11); p = 6 × 10−15.

How common The T allele had a frequency of about 43% in the people studied.

Where it sits Chromosome 3, band 3q28 — between genes, 144.1 kb from TP63.

What each result means

A/A No copy of the version the research linked to Cutaneous squamous cell carcinoma. This is the starting point the study compared everyone against.
A/T One copy of the version the research linked to Cutaneous squamous cell carcinoma. That is a smaller link than two copies.
T/T Two copies of the version the research linked to Cutaneous squamous cell carcinoma. That is the strongest link of the three results. A link in a study is not a diagnosis.
Source

Questions about rs6791479

What is rs6791479?

rs6791479 is a single position in the genome, in or near the TPRG1 gene. Published research associates it with cutaneous squamous cell carcinoma. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

What conditions is rs6791479 linked to?

On MyGeneLog this position is linked to Cutaneous Squamous Cell Carcinoma. The research behind each link, and its sources, are set out on that condition page.

Does having rs6791479 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs6791479 come from?

GWAS Catalog, Nature communications 2020, PMID:32041948. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

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Cutaneous squamous cell carcinoma (rs6791479). MyGeneLog™. https://www.mygenelog.com/variants/rs6791479

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