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Who was studied 60,620 European ancestry cases, 970,216 European ancestry controls.
The effect
Each copy of the G allele carried 1.06 times the odds of Atrial fibrillation (95% confidence interval 1.05-1.08); p = 2 × 10−20.
How common The G allele had a frequency of about 60% in the people studied.
Where it sits Chromosome 3, band 3p22.2 — in an intron of SCN10A.
What each result means
C/CNo copy of the version the research linked to Atrial fibrillation. This is the starting point the study compared everyone against.
C/GOne copy of the version the research linked to Atrial fibrillation. That is a smaller link than two copies.
G/GTwo copies of the version the research linked to Atrial fibrillation. That is the strongest link of the three results. A link in a study is not a diagnosis.
rs6790396 is a single position in the genome, in or near the SCN10A gene. Published research associates it with atrial fibrillation. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.
What conditions is rs6790396 linked to?
On MyGeneLog this position is linked to Atrial Fibrillation. The research behind each link, and its sources, are set out on that condition page.
Does having rs6790396 mean I will get this?
No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.
Where does the information about rs6790396 come from?
GWAS Catalog, Nat Genet 2018, PMID:30061737. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.
0 2832162248Reads by AI crawlersClaude3ChatGPT2Google · Gemini0Perplexity1Meta AI6Microsoft · Copilot2Amazon2Apple4China (ByteDance, Huawei, Baidu…)0Others8Total28Counted by the name each crawler declares; requests found to be impersonating one are left out. Google · Gemini includes Googlebot, the search crawler whose index Google also uses for its AI features. Other search engines and bots are under Others.
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