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Low density lipoprotein cholesterol levels

near SLC2A2 · rs6785233

What the study found

Who was studied 431,167 European ancestry individuals.

The effect Each copy of the T allele shifted the measure 0.0278 lower (95% confidence interval 0.021-0.035); p = 4 × 10−15.

How common The T allele had a frequency of about 92% in the people studied.

Where it sits Chromosome 3, band 3q26.2 — between genes, 12.4 kb from SLC2A2.

What each result means

G/G Published research associates this genotype with typical/baseline likelihood of Low density lipoprotein cholesterol levels — no copies of the reported risk allele.
G/T Published research associates this genotype (one copy of the reported risk allele) with an intermediate association with Low density lipoprotein cholesterol levels.
T/T Published research associates this genotype (two copies of the reported risk allele) with a higher likelihood of Low density lipoprotein cholesterol levels compared to the general population.
Source

Questions about rs6785233

What is rs6785233?

rs6785233 is a single position in the genome, in or near the near SLC2A2 gene. Published research associates it with low density lipoprotein cholesterol levels. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

Does having rs6785233 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs6785233 come from?

GWAS Catalog, Diabetes 2020, PMID:32493714. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

Free to quote and reuse under CC BY 4.0. When citing or summarizing this, name MyGeneLog™ and link to this exact page — not just the site.

Low density lipoprotein cholesterol levels (rs6785233). MyGeneLog™. https://www.mygenelog.com/variants/rs6785233

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