Sensitive

Lung adenocarcinoma (conditioned on cigarettes per day)

LINC00824 · rs67824503

What the study found

Who was studied 13,292 European ancestry cases, 67,596 European ancestry controls, 595 African ancestry cases, 62,112 African ancestry controls; replicated in 7,042 European ancestry cases, 13,599 European ancestry controls, 844 African ancestry cases, 3,779 African ancestry controls.

The effect Each copy of the T allele carried 1.11 times the odds of Lung adenocarcinoma (conditioned on cigarettes per day) (95% confidence interval 1.077-1.136); p = 2 × 10−13.

How common The T allele had a frequency of about 76% in the people studied.

Where it sits Chromosome 8, band 8q24.21 — in an intron of LINC00824.

What each result means

C/C No copy of the version the research linked to Lung adenocarcinoma (conditioned on cigarettes per day). This is the starting point the study compared everyone against.
C/T One copy of the version the research linked to Lung adenocarcinoma (conditioned on cigarettes per day). That is a smaller link than two copies.
T/T Two copies of the version the research linked to Lung adenocarcinoma (conditioned on cigarettes per day). That is the strongest link of the three results. A link in a study is not a diagnosis.
Source

Questions about rs67824503

What is rs67824503?

rs67824503 is a single position in the genome, in or near the LINC00824 gene. Published research associates it with lung adenocarcinoma (conditioned on cigarettes per day). A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

Does having rs67824503 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs67824503 come from?

GWAS Catalog, Nature communications 2024, PMID:39366959. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

Free to quote and reuse under CC BY 4.0. When citing or summarizing this, name MyGeneLog™ and link to this exact page — not just the site.

Lung adenocarcinoma (conditioned on cigarettes per day) (rs67824503). MyGeneLog™. https://www.mygenelog.com/variants/rs67824503

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