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Subjective well-being

near SATB1 · rs6769912

Where this position leads

Condition: Depression (Self-Reported Symptoms)

rs6769912 Condition: Depression (Self-Reported Symptoms) Depression (Self-Reported Symptoms) Condition rs6769912 rs6769912 near SATB1

What the study found

Who was studied 388,538 European ancestry individuals.

The effect Each copy of the C allele shifted the measure 0.018 lower (95% confidence interval 0.012-0.024); p = 3 × 10−8.

How common The C allele had a frequency of about 14% in the people studied.

Where it sits Chromosome 3, band 3p24.3 — in an intron of SATB1-AS1.

What each result means

C/C Two copies of the version the research linked to Subjective well-being. That is the strongest link of the three results. A link in a study is not a diagnosis.
C/T One copy of the version the research linked to Subjective well-being. That is a smaller link than two copies.
T/T No copy of the version the research linked to Subjective well-being. This is the starting point the study compared everyone against.
Source

Questions about rs6769912

What is rs6769912?

rs6769912 is a single position in the genome, in or near the near SATB1 gene. Published research associates it with subjective well-being. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

What conditions is rs6769912 linked to?

On MyGeneLog this position is linked to Depression (Self-Reported Symptoms). The research behind each link, and its sources, are set out on that condition page.

Does having rs6769912 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs6769912 come from?

GWAS Catalog, Nat Genet 2018, PMID:29292387. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

Free to quote and reuse under CC BY 4.0. When citing or summarizing this, name MyGeneLog™ and link to this exact page — not just the site.

Subjective well-being (rs6769912). MyGeneLog™. https://www.mygenelog.com/variants/rs6769912

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