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ICD10 D25: Leiomyoma of uterus

TSPAN12 · rs67679138

What the study found

Who was studied 51,378 European ancestry cases, 243,913 European ancestry controls.

The effect Each copy of the A allele carried 0.95 times the odds of ICD10 D25: Leiomyoma of uterus (95% confidence interval 0.93-0.96); p = 1 × 10−10.

Where it sits Chromosome 7, band 7q31.31 — in an intron of TSPAN12.

What each result means

A/A Two copies of the version the research linked to ICD10 D25: Leiomyoma of uterus. That is the strongest link of the three results. A link in a study is not a diagnosis.
A/G One copy of the version the research linked to ICD10 D25: Leiomyoma of uterus. That is a smaller link than two copies.
G/G No copy of the version the research linked to ICD10 D25: Leiomyoma of uterus. This is the starting point the study compared everyone against.
Source

Questions about rs67679138

What is rs67679138?

rs67679138 is a single position in the genome, in or near the TSPAN12 gene. Published research associates it with icd10 d25: leiomyoma of uterus. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

Does having rs67679138 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs67679138 come from?

GWAS Catalog, Nature medicine 2025, PMID:40069456. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

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ICD10 D25: Leiomyoma of uterus (rs67679138). MyGeneLog™. https://www.mygenelog.com/variants/rs67679138

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