Sensitive

Basal cell carcinoma (PheCode 172.21)

FOXP1 · rs6764416

Where this position leads

Condition: Basal Cell Carcinoma

rs6764416 Condition: Basal Cell Carcinoma Basal Cell Carcinoma Condition rs6764416 rs6764416 FOXP1

What the study found

Who was studied 768 Hispanic or Latin American cases, 58,733 Hispanic or Latin American controls, 31,142 European ancestry cases, 404,406 European ancestry controls.

The effect Each copy of the C allele shifted the measure 0.103 lower (95% confidence interval 0.086-0.119); p = 2 × 10−27.

How common The C allele had a frequency of about 60% in the people studied.

Where it sits Chromosome 3, band 3p13 — in an intron of FOXP1.

What each result means

C/C Two copies of the version the research linked to Basal cell carcinoma (PheCode 172.21). That is the strongest link of the three results. A link in a study is not a diagnosis.
C/T One copy of the version the research linked to Basal cell carcinoma (PheCode 172.21). That is a smaller link than two copies.
T/T No copy of the version the research linked to Basal cell carcinoma (PheCode 172.21). This is the starting point the study compared everyone against.
Source

Questions about rs6764416

What is rs6764416?

rs6764416 is a single position in the genome, in or near the FOXP1 gene. Published research associates it with basal cell carcinoma (phecode 172.21). A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

What conditions is rs6764416 linked to?

On MyGeneLog this position is linked to Basal Cell Carcinoma. The research behind each link, and its sources, are set out on that condition page.

Does having rs6764416 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs6764416 come from?

GWAS Catalog, Science (New York, N.Y.) 2024, PMID:39024449. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

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Basal cell carcinoma (PheCode 172.21) (rs6764416). MyGeneLog™. https://www.mygenelog.com/variants/rs6764416

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