Standard

Urate levels

RREB1 · rs675209

Where this position leads

Condition: Gout

rs675209 Condition: Gout Gout Condition rs675209 rs675209 RREB1

What the study found

Who was studied 28,283 European ancestry individuals; replicated in 22,054 European ancestry individuals.

The effect Each copy of the T allele shifted the measure 4.39 umol/l higher (95% confidence interval 2.98-5.80); p = 1 × 10−9.

How common The T allele had a frequency of about 26% in the people studied.

Where it sits Chromosome 6, band 6p24.3 — between genes, 5.6 kb from RREB1.

What each result means

C/C No copy of the version the research linked to Urate levels. This is the starting point the study compared everyone against.
C/T One copy of the version the research linked to Urate levels. That is a smaller link than two copies.
T/T Two copies of the version the research linked to Urate levels. That is the strongest link of the three results. A link in a study is not a diagnosis.
Source

What people read about alongside this

Papers in Europe PMC whose title or abstract names both this rsID and that subject. A shared paper means somebody wrote about the two together — it is not a claim that this position explains the subject.

Questions about rs675209

What is rs675209?

rs675209 is a single position in the genome, in or near the RREB1 gene. Published research associates it with urate levels. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

What conditions is rs675209 linked to?

On MyGeneLog this position is linked to Gout. The research behind each link, and its sources, are set out on that condition page.

What do people read about alongside rs675209?

Subjects that appear in the title or abstract of the same papers as this rsID include blood sugar and insulin (1 papers). A shared paper means somebody wrote about the two together; it is not a claim that this position explains the topic.

Does having rs675209 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs675209 come from?

GWAS Catalog, Circ Cardiovasc Genet 2010, PMID:20884846. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

Free to quote and reuse under CC BY 4.0. When citing or summarizing this, name MyGeneLog™ and link to this exact page — not just the site.

Urate levels (rs675209). MyGeneLog™. https://www.mygenelog.com/variants/rs675209

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