1 4942127125124Reads by AI crawlersClaude4ChatGPT2Google · Gemini1Perplexity2Meta AI7Microsoft · Copilot1Amazon2Apple5China (ByteDance, Huawei, Baidu…)1ByteDance (Doubao)1Others24Total49Counted by the name each crawler declares; requests found to be impersonating one are left out. Google · Gemini includes Googlebot, the search crawler whose index Google also uses for its AI features. Other search engines and bots are under Others.
Who was studied 407 European ancestry cases, 296 European ancestry controls; replicated in 252 European ancestry cases, 965 European ancestry controls.
The effect
Each copy of the T allele carried 1.69 times the odds of Chronic lymphocytic leukemia (95% confidence interval 1.41-2.01); p = 7 × 10−9.
How common The T allele had a frequency of about 26% in the people studied.
Where it sits Chromosome 6, band 6p21.32 — between genes, 17.9 kb from HLA-DQA1.
What each result means
C/CNo copy of the version the research linked to Chronic lymphocytic leukemia. This is the starting point the study compared everyone against.
C/TOne copy of the version the research linked to Chronic lymphocytic leukemia. That is a smaller link than two copies.
T/TTwo copies of the version the research linked to Chronic lymphocytic leukemia. That is the strongest link of the three results. A link in a study is not a diagnosis.
rs674313 is a single position in the genome, in or near the HLA-DRB5 gene. Published research associates it with chronic lymphocytic leukemia. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.
What conditions is rs674313 linked to?
On MyGeneLog this position is linked to Chronic Lymphocytic Leukaemia. The research behind each link, and its sources, are set out on that condition page.
Does having rs674313 mean I will get this?
No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.
Where does the information about rs674313 come from?
GWAS Catalog, Blood 2010, PMID:21131588. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.
1 4942127125124Reads by AI crawlersClaude4ChatGPT2Google · Gemini1Perplexity2Meta AI7Microsoft · Copilot1Amazon2Apple5China (ByteDance, Huawei, Baidu…)1ByteDance (Doubao)1Others24Total49Counted by the name each crawler declares; requests found to be impersonating one are left out. Google · Gemini includes Googlebot, the search crawler whose index Google also uses for its AI features. Other search engines and bots are under Others.
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