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Chronic lymphocytic leukemia

HLA-DRB5 · rs674313

Stands on its own. Nothing else here links to this position yet — but the page above is the point: what the research found, what each genotype means, and where it came from, in language you can read. Links to conditions, drugs and the senses appear automatically if we write them.

What each result means

C/C Published research associates this genotype with typical/baseline likelihood of Chronic lymphocytic leukemia — no copies of the reported risk allele. (GWAS Catalog, Blood 2010, PMID:21131588)

C/T Published research associates this genotype (one copy of the reported risk allele) with an intermediate association with Chronic lymphocytic leukemia. (GWAS Catalog, Blood 2010, PMID:21131588)

T/T Published research associates this genotype (two copies of the reported risk allele) with a higher likelihood of Chronic lymphocytic leukemia compared to the general population. (GWAS Catalog, Blood 2010, PMID:21131588)

Source: GWAS Catalog, Blood 2010, PMID:21131588

Questions about rs674313

What is rs674313?

rs674313 is a single position in the genome, in or near the HLA-DRB5 gene. Published research associates it with chronic lymphocytic leukemia. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

Does having rs674313 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs674313 come from?

GWAS Catalog, Blood 2010, PMID:21131588. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

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