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Who was studied 250 Korean ancestry cases, 296 Korean ancestry controls.
The effect
Each copy of the C allele carried 4.00 times the odds of Intracranial aneurysm (95% confidence interval 2.78-5.56); p = 4 × 10−14.
How common The C allele had a frequency of about 63% in the people studied.
Where it sits Chromosome 2, band 2p25.1 — in an intron of RNF144A.
What each result means
C/CTwo copies of the version the research linked to Intracranial aneurysm. That is the strongest link of the three results. A link in a study is not a diagnosis.
C/TOne copy of the version the research linked to Intracranial aneurysm. That is a smaller link than two copies.
T/TNo copy of the version the research linked to Intracranial aneurysm. This is the starting point the study compared everyone against.
Journal of clinical medicine · 2019 · PMID 30823506 · open access
Questions about rs6741819
What is rs6741819?
rs6741819 is a single position in the genome, in or near the RNF144A gene. Published research associates it with intracranial aneurysm. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.
What conditions is rs6741819 linked to?
On MyGeneLog this position is linked to Intracranial Aneurysm. The research behind each link, and its sources, are set out on that condition page.
Does having rs6741819 mean I will get this?
No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.
Where does the information about rs6741819 come from?
GWAS Catalog, Journal of clinical medicine 2019, PMID:30823506. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.
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