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Who was studied 49,905 European ancestry cases, 752,392 European ancestry controls, 626 Hispanic or Latin American cases, 9,842 Hispanic or Latin American controls.
The effect
The reported allele is C; the catalogue records no effect size
; p = 3 × 10−10.
Where it sits Chromosome 2, band 2p25.1 — in an intron of GRHL1.
What each result means
C/CTwo copies of the version the research linked to Basal cell carcinoma. That is the strongest link of the three results. A link in a study is not a diagnosis.
C/GOne copy of the version the research linked to Basal cell carcinoma. That is a smaller link than two copies.
G/GNo copy of the version the research linked to Basal cell carcinoma. This is the starting point the study compared everyone against.
Communications biology · 2024 · PMID 38182794 · open access
Questions about rs6741117
What is rs6741117?
rs6741117 is a single position in the genome, in or near the GRHL1 gene. Published research associates it with basal cell carcinoma. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.
What conditions is rs6741117 linked to?
On MyGeneLog this position is linked to Basal Cell Carcinoma. The research behind each link, and its sources, are set out on that condition page.
Does having rs6741117 mean I will get this?
No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.
Where does the information about rs6741117 come from?
GWAS Catalog, Communications biology 2024, PMID:38182794. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.
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