Standard

Body mass index

ICA1L · rs6733972

Where this position leads

Conditions: Childhood Body Mass Index, Obesity and Body Weight

rs6733972 Condition: Childhood Body Mass Index Childhood Body Mass Index Condition Condition: Obesity and Body Weight Obesity and Body Weight Condition rs6733972 rs6733972 ICA1L

What the study found

Who was studied 650,000 European ancestry individuals.

The effect Each copy of the T allele shifted the measure 0.012 lower (95% confidence interval 0.0085-0.0155); p = 2 × 10−11.

How common The T allele had a frequency of about 51% in the people studied.

Where it sits Chromosome 2, band 2q33.2 — in an intron of ICA1L.

What each result means

C/C No copy of the version the research linked to Body mass index. This is the starting point the study compared everyone against.
C/T One copy of the version the research linked to Body mass index. That is a smaller link than two copies.
T/T Two copies of the version the research linked to Body mass index. That is the strongest link of the three results. A link in a study is not a diagnosis.
Source

Questions about rs6733972

What is rs6733972?

rs6733972 is a single position in the genome, in or near the ICA1L gene. Published research associates it with body mass index. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

What conditions is rs6733972 linked to?

On MyGeneLog this position is linked to Childhood Body Mass Index, Obesity and Body Weight. The research behind each link, and its sources, are set out on that condition page.

Does having rs6733972 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs6733972 come from?

GWAS Catalog, Nature genetics 2024, PMID:39375568. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

Free to quote and reuse under CC BY 4.0. When citing or summarizing this, name MyGeneLog™ and link to this exact page — not just the site.

Body mass index (rs6733972). MyGeneLog™. https://www.mygenelog.com/variants/rs6733972

← See all variants