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Immune response to smallpox vaccine (IL-6)

LTBP1 · rs6728021

Stands on its own. Nothing else here links to this position yet — but the page above is the point: what the research found, what each genotype means, and where it came from, in language you can read. Links to conditions, drugs and the senses appear automatically if we write them.

What each result means

A/A Published research associates this genotype with typical/baseline likelihood of Immune response to smallpox vaccine (IL-6) — no copies of the reported risk allele. (GWAS Catalog, Hum Genet 2012, PMID:22610502)

A/G Published research associates this genotype (one copy of the reported risk allele) with an intermediate association with Immune response to smallpox vaccine (IL-6). (GWAS Catalog, Hum Genet 2012, PMID:22610502)

G/G Published research associates this genotype (two copies of the reported risk allele) with a higher likelihood of Immune response to smallpox vaccine (IL-6) compared to the general population. (GWAS Catalog, Hum Genet 2012, PMID:22610502)

Source: GWAS Catalog, Hum Genet 2012, PMID:22610502

Questions about rs6728021

What is rs6728021?

rs6728021 is a single position in the genome, in or near the LTBP1 gene. Published research associates it with immune response to smallpox vaccine (il-6). A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

Does having rs6728021 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs6728021 come from?

GWAS Catalog, Hum Genet 2012, PMID:22610502. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

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