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Total bilirubin in pregnancy

UGT1A9 · rs6723506

What the study found

Who was studied 94,620 Chinese ancestry individuals; replicated in 46,187 Chinese ancestry individuals.

The effect Each copy of the G allele shifted the measure 0.548 higher (95% confidence interval 0.51-0.59); p = 8 × 10−139.

How common The G allele had a frequency of about 4% in the people studied.

Where it sits Chromosome 2, band 2q37.1 — in an intron of UGT1A9.

What each result means

A/A No copy of the version the research linked to Total bilirubin in pregnancy. This is the starting point the study compared everyone against.
A/G One copy of the version the research linked to Total bilirubin in pregnancy. That is a smaller link than two copies.
G/G Two copies of the version the research linked to Total bilirubin in pregnancy. That is the strongest link of the three results. A link in a study is not a diagnosis.
Source

Questions about rs6723506

What is rs6723506?

rs6723506 is a single position in the genome, in or near the UGT1A9 gene. Published research associates it with total bilirubin in pregnancy. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

Does having rs6723506 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs6723506 come from?

GWAS Catalog, Nature genetics 2026, PMID:42509370. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

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Total bilirubin in pregnancy (rs6723506). MyGeneLog™. https://www.mygenelog.com/variants/rs6723506

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