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Biological sex

PDE11A · rs6718702

What the study found

Who was studied 1,301,549 European ancestry cases, 1,160,583 European ancestry controls.

The effect Each copy of the T allele shifted the measure 0.0151 lower (95% confidence interval 0.011-0.019); p = 3 × 10−12.

Where it sits Chromosome 2, band 2q31.2 — in an intron of PDE11A.

What each result means

C/C No copy of the version the research linked to Biological sex. This is the starting point the study compared everyone against.
C/T One copy of the version the research linked to Biological sex. That is a smaller link than two copies.
T/T Two copies of the version the research linked to Biological sex. That is the strongest link of the three results. A link in a study is not a diagnosis.
Source

Questions about rs6718702

What is rs6718702?

rs6718702 is a single position in the genome, in or near the PDE11A gene. Published research associates it with biological sex. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

Does having rs6718702 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs6718702 come from?

GWAS Catalog, Nature genetics 2021, PMID:33888908. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

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Biological sex (rs6718702). MyGeneLog™. https://www.mygenelog.com/variants/rs6718702

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