Standard

CCL18 protein levels

near EML4-AS1 · rs6715862

Where this position leads

Condition: Celiac Disease

rs6715862 Condition: Celiac Disease Celiac Disease Condition rs6715862 rs6715862 near EML4-AS1

What the study found

Who was studied 47,745 European ancestry individuals.

The effect Each copy of the G allele shifted the measure 0.0683 lower (95% confidence interval 0.057-0.079); p = 1 × 10−38.

How common The G allele had a frequency of about 50% in the people studied.

Where it sits Chromosome 2, band 2p21 — between genes, 41 kb from EML4-AS1.

What each result means

A/A No copy of the version the research linked to CCL18 protein levels. This is the starting point the study compared everyone against.
A/G One copy of the version the research linked to CCL18 protein levels. That is a smaller link than two copies.
G/G Two copies of the version the research linked to CCL18 protein levels. That is the strongest link of the three results. A link in a study is not a diagnosis.
Source

Questions about rs6715862

What is rs6715862?

rs6715862 is a single position in the genome, in or near the near EML4-AS1 gene. Published research associates it with ccl18 protein levels. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

What conditions is rs6715862 linked to?

On MyGeneLog this position is linked to Celiac Disease. The research behind each link, and its sources, are set out on that condition page.

Does having rs6715862 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs6715862 come from?

GWAS Catalog, Nature genetics 2025, PMID:39789286. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

Free to quote and reuse under CC BY 4.0. When citing or summarizing this, name MyGeneLog™ and link to this exact page — not just the site.

CCL18 protein levels (rs6715862). MyGeneLog™. https://www.mygenelog.com/variants/rs6715862

← See all variants