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CD28- CD4-CD8- T cell Absolute Count

CD8B · rs6710361

What the study found

Who was studied 3,408 Sardinian (founder/genetic isolate) ancestry individuals.

The effect Each copy of the A allele shifted the measure 0.192 higher (95% confidence interval 0.13-0.25); p = 1 × 10−9.

How common The A allele had a frequency of about 20% in the people studied.

Where it sits Chromosome 2, band 2p11.2 — in an intron of CD8B.

What each result means

A/A Two copies of the version the research linked to CD28- CD4-CD8- T cell Absolute Count. That is the strongest link of the three results. A link in a study is not a diagnosis.
A/G One copy of the version the research linked to CD28- CD4-CD8- T cell Absolute Count. That is a smaller link than two copies.
G/G No copy of the version the research linked to CD28- CD4-CD8- T cell Absolute Count. This is the starting point the study compared everyone against.
Source

Questions about rs6710361

What is rs6710361?

rs6710361 is a single position in the genome, in or near the CD8B gene. Published research associates it with cd28- cd4-cd8- t cell absolute count. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

Does having rs6710361 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs6710361 come from?

GWAS Catalog, Nature genetics 2020, PMID:32929287. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

Free to quote and reuse under CC BY 4.0. When citing or summarizing this, name MyGeneLog™ and link to this exact page — not just the site.

CD28- CD4-CD8- T cell Absolute Count (rs6710361). MyGeneLog™. https://www.mygenelog.com/variants/rs6710361

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