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Sensitive

Inflammatory bowel disease

IL18RAP · rs6708413

Where this position leads

Condition: Inflammatory Bowel Disease

rs6708413 Condition: Inflammatory Bowel Disease Inflammatory Bowel Disease Condition rs6708413 rs6708413 IL18RAP

What each result means

A/A Published research associates this genotype with typical/baseline likelihood of Inflammatory bowel disease — no copies of the reported risk allele.
A/G Published research associates this genotype (one copy of the reported risk allele) with an intermediate association with Inflammatory bowel disease.
G/G Published research associates this genotype (two copies of the reported risk allele) with a higher likelihood of Inflammatory bowel disease compared to the general population.
Source
Association analyses identify 38 susceptibility loci for inflammatory bowel disease and highlight shared genetic risk across populations
Liu JZ, van Sommeren S, Huang H, Ng SC, Alberts R, Takahashi A, Ripke S, Lee JC, Jostins L, Shah T, Abedian S, Cheon JH
and 28 more — show all
Cho J, Dayani NE, Franke L, Fuyuno Y, Hart A, Juyal RC, Juyal G, Kim WH, Morris AP, Poustchi H, Newman WG, Midha V, Orchard TR, Vahedi H, Sood A, Sung JY, Malekzadeh R, Westra HJ, Yamazaki K, Yang SK, Barrett JC, Alizadeh BZ, Parkes M, Bk T, Daly MJ, Kubo M, Anderson CA, Weersma RK
International Multiple Sclerosis Genetics Consortium · International IBD Genetics Consortium
Nature genetics · 2015 · PMID 26192919

Questions about rs6708413

What is rs6708413?

rs6708413 is a single position in the genome, in or near the IL18RAP gene. Published research associates it with inflammatory bowel disease. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

What conditions is rs6708413 linked to?

On MyGeneLog this position is linked to Inflammatory Bowel Disease. The research behind each link, and its sources, are set out on that condition page.

Does having rs6708413 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs6708413 come from?

GWAS Catalog, Nat Genet 2015, PMID:26192919. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

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