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Intraocular pressure

NPLOC4 · rs67050149

Stands on its own. Nothing else here links to this position yet — but the page above is the point: what the research found, what each genotype means, and where it came from, in language you can read. Links to conditions, drugs and the senses appear automatically if we write them.

What each result means

A/A Published research associates this genotype with typical/baseline likelihood of Intraocular pressure — no copies of the reported risk allele.

A/C Published research associates this genotype (one copy of the reported risk allele) with an intermediate association with Intraocular pressure.

C/C Published research associates this genotype (two copies of the reported risk allele) with a higher likelihood of Intraocular pressure compared to the general population.

Source

Genome-wide association analyses identify new loci influencing intraocular pressure

Gao XR, Huang H, Nannini DR, Fan F, Kim H

Human molecular genetics · 2018 · PMID 29617998

Questions about rs67050149

What is rs67050149?

rs67050149 is a single position in the genome, in or near the NPLOC4 gene. Published research associates it with intraocular pressure. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

Does having rs67050149 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs67050149 come from?

GWAS Catalog, Hum Mol Genet 2018, PMID:29617998. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

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