Sensitive

Coronary artery disease

DDX59 · rs6700559

Where this position leads

Condition: Coronary Artery Disease

rs6700559 Condition: Coronary Artery Disease Coronary Artery Disease Condition rs6700559 rs6700559 DDX59

What the study found

Who was studied up to 122,733 cases, up to 424,528 controls.

The effect Each copy of the T allele shifted the measure 0.0284 lower (95% confidence interval 0.019-0.038); p = 2 × 10−8.

How common The T allele had a frequency of about 47% in the people studied.

Where it sits Chromosome 1, band 1q32.1 — in an intron of DDX59-AS1.

What each result means

C/C Published research associates this genotype with typical/baseline likelihood of Coronary artery disease — no copies of the reported risk allele.
C/T Published research associates this genotype (one copy of the reported risk allele) with an intermediate association with Coronary artery disease.
T/T Published research associates this genotype (two copies of the reported risk allele) with a higher likelihood of Coronary artery disease compared to the general population.
Source

Questions about rs6700559

What is rs6700559?

rs6700559 is a single position in the genome, in or near the DDX59 gene. Published research associates it with coronary artery disease. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

What conditions is rs6700559 linked to?

On MyGeneLog this position is linked to Coronary Artery Disease. The research behind each link, and its sources, are set out on that condition page.

Does having rs6700559 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs6700559 come from?

GWAS Catalog, Circ Res 2017, PMID:29212778. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

Free to quote and reuse under CC BY 4.0. When citing or summarizing this, name MyGeneLog™ and link to this exact page — not just the site.

Coronary artery disease (rs6700559). MyGeneLog™. https://www.mygenelog.com/variants/rs6700559

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