LEPR · rs6698653
Where this position leads
Condition: C-Reactive Protein Levels
What the study found
Who was studied 418,642 British ancestry individuals.
The effect Each copy of the T allele shifted the measure 0.0621 lower (95% confidence interval 0.058-0.066); p = 4 × 10−209.
How common The T allele had a frequency of about 52% in the people studied.
Where it sits Chromosome 1, band 1p31.3 — in an intron of LEPR.
rs6698653 is a single position in the genome, in or near the LEPR gene. Published research associates it with c-reactive protein levels. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.
On MyGeneLog this position is linked to C-Reactive Protein Levels. The research behind each link, and its sources, are set out on that condition page.
No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.
GWAS Catalog, European journal of epidemiology 2020, PMID:31900758. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.
Free to quote and reuse under CC BY 4.0. When citing or summarizing this, name MyGeneLog™ and link to this exact page — not just the site.
C-reactive protein levels (rs6698653). MyGeneLog™. https://www.mygenelog.com/variants/rs6698653