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Stands on its own.
Nothing else here links to this position yet — but the page above is the point: what the
research found, what each genotype means, and where it came from, in language you can
read. Links to conditions, drugs and the senses appear automatically if we write them.
What the study found
Who was studied 18,883 European ancestry individuals.
The effect
Each copy of the C allele shifted the measure 0.296 lower (95% confidence interval 0.25-0.35); p = 5 × 10−31.
Where it sits Chromosome 11, band 11q12.1 — between genes, 1.8 kb from OR5M8.
What each result means
A/ANo copy of the version the research linked to Odor identification (pineapple). This is the starting point the study compared everyone against.
A/COne copy of the version the research linked to Odor identification (pineapple). That is a smaller link than two copies.
C/CTwo copies of the version the research linked to Odor identification (pineapple). That is the strongest link of the three results. A link in a study is not a diagnosis.
Nature communications · 2025 · PMID 40593737 · open access
Questions about rs669453
What is rs669453?
rs669453 is a single position in the genome, in or near the near OR5M8 gene. Published research associates it with odor identification (pineapple). A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.
Does having rs669453 mean I will get this?
No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.
Where does the information about rs669453 come from?
GWAS Catalog, Nature communications 2025, PMID:40593737. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.
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