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Visceral adipose tissue/subcutaneous adipose tissue ratio adjusted for BMI

LYPLAL1 · rs6689335

What the study found

Who was studied 7,618 European ancestry women, 7,050 European ancestry men, 2,205 African American women, 1,324 African American men..

The effect Each copy of the T allele shifted the measure 5.53 z-score lower (95% confidence interval -); p = 3 × 10−8.

How common The T allele had a frequency of about 59% in the people studied.

Where it sits Chromosome 1, band 1q41 — in an intron of LYPLAL1-AS1.

What each result means

C/C No copy of the version the research linked to Visceral adipose tissue/subcutaneous adipose tissue ratio adjusted for BMI. This is the starting point the study compared everyone against.
C/T One copy of the version the research linked to Visceral adipose tissue/subcutaneous adipose tissue ratio adjusted for BMI. That is a smaller link than two copies.
T/T Two copies of the version the research linked to Visceral adipose tissue/subcutaneous adipose tissue ratio adjusted for BMI. That is the strongest link of the three results. A link in a study is not a diagnosis.
Source

Questions about rs6689335

What is rs6689335?

rs6689335 is a single position in the genome, in or near the LYPLAL1 gene. Published research associates it with visceral adipose tissue/subcutaneous adipose tissue ratio adjusted for bmi. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

Does having rs6689335 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs6689335 come from?

GWAS Catalog, Nat Genet 2016, PMID:27918534. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

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Visceral adipose tissue/subcutaneous adipose tissue ratio adjusted for BMI (rs6689335). MyGeneLog™. https://www.mygenelog.com/variants/rs6689335

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