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Angioedema in response to angiotensin-converting enzyme inhibitor

near F5 · rs6687813

What the study found

Who was studied 1,060 European ancestry cases, 77,799 European ancestry controls, 63 African American or Afro-Caribbean cases, 149 African American or Afro-Caribbean controls.

The effect Each copy of the A allele carried 1.70 times the odds of Angioedema in response to angiotensin-converting enzyme inhibitor (95% confidence interval 1.54-1.86); p = 1 × 10−10.

Where it sits Chromosome 1, band 1q24.2 — between genes, 3.6 kb from F5.

What each result means

A/A Two copies of the version the research linked to Angioedema in response to angiotensin-converting enzyme inhibitor. That is the strongest link of the three results. A link in a study is not a diagnosis.
A/C One copy of the version the research linked to Angioedema in response to angiotensin-converting enzyme inhibitor. That is a smaller link than two copies.
C/C No copy of the version the research linked to Angioedema in response to angiotensin-converting enzyme inhibitor. This is the starting point the study compared everyone against.
Source

Questions about rs6687813

What is rs6687813?

rs6687813 is a single position in the genome, in or near the near F5 gene. Published research associates it with angioedema in response to angiotensin-converting enzyme inhibitor. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

Does having rs6687813 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs6687813 come from?

GWAS Catalog, The Journal of allergy and clinical immunology 2024, PMID:38300190. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

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Angioedema in response to angiotensin-converting enzyme inhibitor (rs6687813). MyGeneLog™. https://www.mygenelog.com/variants/rs6687813

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