Sensitive

Colorectal cancer

DUSP10 · rs6687758

Where this position leads

Condition: Colorectal Cancer

rs6687758 Condition: Colorectal Cancer Colorectal Cancer Condition rs6687758 rs6687758 DUSP10

What the study found

Who was studied 3,334 European ancestry cases, 4,628 European ancestry controls; replicated in 14,851 European ancestry cases, 15,569 European ancestry controls.

The effect Each copy of the G allele carried 1.09 times the odds of Colorectal cancer (95% confidence interval 1.06-1.12); p = 2 × 10−9.

Where it sits Chromosome 1, band 1q41 — in an intron of LINC01705.

What each result means

A/A No copy of the version the research linked to Colorectal cancer. This is the starting point the study compared everyone against.
A/G One copy of the version the research linked to Colorectal cancer. That is a smaller link than two copies.
G/G Two copies of the version the research linked to Colorectal cancer. That is the strongest link of the three results. A link in a study is not a diagnosis.
Source

What people read about alongside this

Papers in Europe PMC whose title or abstract names both this rsID and that subject. A shared paper means somebody wrote about the two together — it is not a claim that this position explains the subject.

Questions about rs6687758

What is rs6687758?

rs6687758 is a single position in the genome, in or near the DUSP10 gene. Published research associates it with colorectal cancer. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

What conditions is rs6687758 linked to?

On MyGeneLog this position is linked to Colorectal Cancer. The research behind each link, and its sources, are set out on that condition page.

What do people read about alongside rs6687758?

Subjects that appear in the title or abstract of the same papers as this rsID include alcohol and the flush (1 papers), exercise and muscle (1 papers). A shared paper means somebody wrote about the two together; it is not a claim that this position explains the topic.

Does having rs6687758 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs6687758 come from?

GWAS Catalog, Nat Genet 2010, PMID:20972440. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

Free to quote and reuse under CC BY 4.0. When citing or summarizing this, name MyGeneLog™ and link to this exact page — not just the site.

Colorectal cancer (rs6687758). MyGeneLog™. https://www.mygenelog.com/variants/rs6687758

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