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Concentration of very large HDL particles

LINC01344 · rs6687315

What the study found

Who was studied 98,316 European ancestry individuals.

The effect Each copy of the A allele shifted the measure 8.33e-05 lower (95% confidence interval 0.00006-0.00011); p = 9 × 10−11.

How common The A allele had a frequency of about 32% in the people studied.

Where it sits Chromosome 1, band 1q25.3 — in an intron of LINC01344.

What each result means

A/A Two copies of the version the research linked to Concentration of very large HDL particles. That is the strongest link of the three results. A link in a study is not a diagnosis.
A/G One copy of the version the research linked to Concentration of very large HDL particles. That is a smaller link than two copies.
G/G No copy of the version the research linked to Concentration of very large HDL particles. This is the starting point the study compared everyone against.
Source

Questions about rs6687315

What is rs6687315?

rs6687315 is a single position in the genome, in or near the LINC01344 gene. Published research associates it with concentration of very large hdl particles. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

Does having rs6687315 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs6687315 come from?

GWAS Catalog, Ophthalmology science 2024, PMID:39091897. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

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Concentration of very large HDL particles (rs6687315). MyGeneLog™. https://www.mygenelog.com/variants/rs6687315

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