Standard

Eosinophil count

JAK1 · rs6682237

Where this position leads

Condition: Blood Cell Counts

rs6682237 Condition: Blood Cell Counts Blood Cell Counts Condition rs6682237 rs6682237 JAK1

What the study found

Who was studied 583,850 African American or Afro-Caribbean, African ancestry, European ancestry, East Asian ancestry, Hispanic or Latin American and South Asian ancestry individuals.

The effect The reported allele is C; the catalogue records no effect size ; p = 2 × 10−34.

How common The C allele had a frequency of about 16% in the people studied.

Where it sits Chromosome 1, band 1p31.3 — in an intron of JAK1.

What each result means

A/A No copy of the version the research linked to Eosinophil count. This is the starting point the study compared everyone against.
A/C One copy of the version the research linked to Eosinophil count. That is a smaller link than two copies.
C/C Two copies of the version the research linked to Eosinophil count. That is the strongest link of the three results. A link in a study is not a diagnosis.
Source

Questions about rs6682237

What is rs6682237?

rs6682237 is a single position in the genome, in or near the JAK1 gene. Published research associates it with eosinophil count. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

What conditions is rs6682237 linked to?

On MyGeneLog this position is linked to Blood Cell Counts. The research behind each link, and its sources, are set out on that condition page.

Does having rs6682237 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs6682237 come from?

GWAS Catalog, Cell 2020, PMID:32888493. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

Free to quote and reuse under CC BY 4.0. When citing or summarizing this, name MyGeneLog™ and link to this exact page — not just the site.

Eosinophil count (rs6682237). MyGeneLog™. https://www.mygenelog.com/variants/rs6682237

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