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Platelet distribution width

GFI1B · rs667805

What the study found

Who was studied 408,112 British individuals.

The effect Each copy of the G allele shifted the measure 0.0249 lower (95% confidence interval 0.018-0.031); p = 3 × 10−14.

How common The G allele had a frequency of about 14% in the people studied.

Where it sits Chromosome 9, band 9q34.13 — in the 3′ untranslated region of GFI1B.

What ClinVar records

Classification Benign; criteria provided, multiple submitters, no conflicts (2 of 4 stars, 2 submitters), last evaluated 2021-06-19. ClinVar record 1295072 NM_001377304.1(GFI1B):c.*256A>G

What this is ClinVar's aggregate record for this position (as of its 2026-10-19 release), not a result about you. A classification describes the variant against the condition named, as laboratories submitted it. Whether a person carries this variant, and what that would mean for them, is a question for a clinical test and a genetic counsellor.

What each result means

A/A No copy of the version the research linked to Platelet distribution width. This is the starting point the study compared everyone against.
A/G One copy of the version the research linked to Platelet distribution width. That is a smaller link than two copies.
G/G Two copies of the version the research linked to Platelet distribution width. That is the strongest link of the three results. A link in a study is not a diagnosis.
Source

Questions about rs667805

What is rs667805?

rs667805 is a single position in the genome, in or near the GFI1B gene. Published research associates it with platelet distribution width. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

Does having rs667805 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs667805 come from?

GWAS Catalog, Cell 2020, PMID:32888494. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

Free to quote and reuse under CC BY 4.0. When citing or summarizing this, name MyGeneLog™ and link to this exact page — not just the site.

Platelet distribution width (rs667805). MyGeneLog™. https://www.mygenelog.com/variants/rs667805

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