Standard

Post bronchodilator FEV1/FVC ratio

CHRNA5 · rs667282

Where this position leads

Condition: Pulmonary Function (Lung Capacity)

rs667282 Condition: Pulmonary Function (Lung Capacity) Pulmonary Function (Lung Capacity) Condition rs667282 rs667282 CHRNA5

What each result means

C/C Published research associates this genotype with typical/baseline likelihood of Post bronchodilator FEV1/FVC ratio — no copies of the reported risk allele.
C/T Published research associates this genotype (one copy of the reported risk allele) with an intermediate association with Post bronchodilator FEV1/FVC ratio.
T/T Published research associates this genotype (two copies of the reported risk allele) with a higher likelihood of Post bronchodilator FEV1/FVC ratio compared to the general population.
Source

Questions about rs667282

What is rs667282?

rs667282 is a single position in the genome, in or near the CHRNA5 gene. Published research associates it with post bronchodilator fev1/fvc ratio. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

What conditions is rs667282 linked to?

On MyGeneLog this position is linked to Pulmonary Function (Lung Capacity). The research behind each link, and its sources, are set out on that condition page.

Does having rs667282 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs667282 come from?

GWAS Catalog, BMC Genet 2015, PMID:26634245. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

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