Standard

Triglyceride levels in chylomicrons and extremely large VLDL

near ZC3H11B · rs6669360

Where this position leads

Condition: Cholesterol (LDL, HDL and Total)

rs6669360 Condition: Cholesterol (LDL, HDL and Total) Cholesterol (LDL, HDL and Total) Condition rs6669360 rs6669360 near ZC3H11B

What the study found

Who was studied 434,646 British ancestry individuals, 8,796 British Central/South Asian individuals, 6,573 British African individuals.

The effect Each copy of the T allele shifted the measure 0.02 mmol/L lower (95% confidence interval 0.02-0.02); p = 2 × 10−16.

Where it sits Chromosome 1, band 1q41 — in an intron of LYPLAL1-AS1.

What each result means

A/A No copy of the version the research linked to Triglyceride levels in chylomicrons and extremely large VLDL. This is the starting point the study compared everyone against.
A/T One copy of the version the research linked to Triglyceride levels in chylomicrons and extremely large VLDL. That is a smaller link than two copies.
T/T Two copies of the version the research linked to Triglyceride levels in chylomicrons and extremely large VLDL. That is the strongest link of the three results. A link in a study is not a diagnosis.
Source

Questions about rs6669360

What is rs6669360?

rs6669360 is a single position in the genome, in or near the near ZC3H11B gene. Published research associates it with triglyceride levels in chylomicrons and extremely large vldl. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

What conditions is rs6669360 linked to?

On MyGeneLog this position is linked to Cholesterol (LDL, HDL and Total). The research behind each link, and its sources, are set out on that condition page.

Does having rs6669360 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs6669360 come from?

GWAS Catalog, Nature genetics 2025, PMID:41044249. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

Free to quote and reuse under CC BY 4.0. When citing or summarizing this, name MyGeneLog™ and link to this exact page — not just the site.

Triglyceride levels in chylomicrons and extremely large VLDL (rs6669360). MyGeneLog™. https://www.mygenelog.com/variants/rs6669360

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