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High-sensitivity C-reactive protein levels in HIV infection

CRP · rs6667499

Where this position leads

Condition: C-Reactive Protein Levels

rs6667499 Condition: C-Reactive Protein Levels C-Reactive Protein Levels Condition rs6667499 rs6667499 CRP

What the study found

Who was studied 4,675 European ancestry individuals, 1,732 African ancestry individuals, 645 Admixed American individuals.

The effect Each copy of the A allele shifted the measure 0.569 higher (95% confidence interval 0.46-0.68); p = 2 × 10−25.

How common The A allele had a frequency of about 4% in the people studied.

Where it sits Chromosome 1, band 1q23.2 — between genes, 2.3 kb from CRPP1.

What each result means

A/A Two copies of the version the research linked to High-sensitivity C-reactive protein levels in HIV infection. That is the strongest link of the three results. A link in a study is not a diagnosis.
A/G One copy of the version the research linked to High-sensitivity C-reactive protein levels in HIV infection. That is a smaller link than two copies.
G/G No copy of the version the research linked to High-sensitivity C-reactive protein levels in HIV infection. This is the starting point the study compared everyone against.
Source

Questions about rs6667499

What is rs6667499?

rs6667499 is a single position in the genome, in or near the CRP gene. Published research associates it with high-sensitivity c-reactive protein levels in hiv infection. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

What conditions is rs6667499 linked to?

On MyGeneLog this position is linked to C-Reactive Protein Levels. The research behind each link, and its sources, are set out on that condition page.

Does having rs6667499 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs6667499 come from?

GWAS Catalog, AIDS (London, England) 2021, PMID:33095540. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

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High-sensitivity C-reactive protein levels in HIV infection (rs6667499). MyGeneLog™. https://www.mygenelog.com/variants/rs6667499

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